Evaluating the Movement of Pharmaceuticals in Soil, Groundwater, and Surface Water at a Municipal Wastewater Land Application Site. Andrew McEachran, NCSU Dept. of Natural Resources. Summary: The occurrence and fate of pharmaceutical and personal care products (PPCPs) associated with municipal wastewater is of increasing importance in the literature due to documented effects on wildlife, ecosystems, and potentially humans. One yet undefined source of entry into the environment of PPCPs is via the land application of municipal wastewater onto permitted lands, an alternative wastewater treatment and disposal method that is cost effective and provides benefits in terms of groundwater reinfiltration and ecological services . Previous research in our lab quantified PPCPs in the groundwater below a wastewater land application facility. The objective of this study is to more fully determine the extent to which PPCPs are mitigated by or exported from managed tree plantations irrigated with municipal wastewater by quantifying PPCPs in the irrigated wastewater, soil, groundwater, and surface water. The study site is a municipality that land-applies primary treated wastewater onto 3,000 acres of managed hardwood and pine plantations. A suite of 33 PPCPs were targeted in the analysis, which consisted of grab sampling of groundwater and surface throughout the site as well as upstream and downstream. Additionally, two soil depths at four locations were sampled and PPCPs were extracted from both the aqueous and solid fraction of the soil samples. All extracted samples were concentrated and cleaned-up via solid phase extraction (SPE) and separation, detection, and quantification occurred via LC-MS/MS. The results of this study provide important documentation for PPCP fate and transport in forested land application systems and potentially advance the use of sustainable technologies for energy production and environmental protection in coupled natural human systems.